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by LifePharm Inc

Study: Supplements Improve Conception Rates for Couples Struggling to Conceive

infertility conception conceive supplements

Infertility can be a difficult and emotional experience for couples. Couples may feel a sense of loss, particularly if they have been trying to have a child for a long time, and may grieve the absence of the opportunity to experience pregnancy, childbirth, and parenthood.

In this article, we first discuss what infertility is, with a focus on male infertility, its effects, standard treatment procedures, and the advantages and disadvantages of each procedure. The article hones in on how LAMININE and OMEGA+++ supplements can help male patients with symptoms of infertility, according to a study.

Male Infertility and its Causes

Infertility is defined by the Centers for Disease Control and Prevention (CDC) as a couple’s inability to conceive despite having frequent intercourse without contraceptive use for at least a year. Infertility affects around 8–12% of couples worldwide, and it can affect both men and women. In about 40% of cases, infertility is caused solely by male factors. In the US, around 126 out of 100,000 men aged 25 to 34 years old seek male infertility services, which accounts for the highest utilization of the services across all ages, followed by men aged 35 to 44 years old, with 83 out of 100,000 men.

Male infertility may be caused externally by environmental factors or internally by anatomic, hormonal, or genetic factors. Environmental factors, to name a few, include overheating, whereby wearing tight clothing or engaging in activities that raise the temperature of the scrotum (such as hot tub use or prolonged sitting) can affect sperm production and function. Psychological stresses, especially prolonged stress, can affect testosterone levels and lower sperm count. Substance abuse and alcohol consumption have also been significantly linked to fertility problems in men, producing a variety of symptoms such as low sperm count and abnormal sperm shape and motility.

For internal factors, anatomic causes include reproductive diseases such as sexually transmitted infections, prostatitis (inflammation of the prostate gland), and orchitis (inflammation of the testicles). Hormonal disorders, such as increased prolactin levels and androgen insensitivity syndrome, and genetic disorders, such as polymorphism of genes and point mutations, can also play a part in infertility. Any of these disorders or diseases can affect how the body produces, stores, and transports sperm.

Standards and Treatment Procedures for Male Infertility

There are several treatment options available for men with infertility, depending on the underlying cause of the fertility problems. Some common treatments for male infertility include the following.

Lifestyle changes

Lifestyle changes are frequently recommended not only for their fertility benefits but also for their overall health benefits. Patients may be advised to maintain a regular schedule of work and rest, eat healthily, have regular intercourse, and get checked and treated for any comorbid disease. Exercise regimens should be modified so that extreme lower body stress and overheating are avoided. Patients may also be advised to avoid feeling depressed, anxious, or neurotic to the extent that they are able. 

Medications

In some cases, medications can help to improve sperm production or motility or treat hormonal imbalances that may be contributing to fertility problems. Using medications to treat male infertility enables the patient to target the specific underlying causes of fertility problems, provides them with the convenience of oral or injectable administration, and has the potential for relatively quick and effective results. However, medications can also have potential side effects and may not be suitable for all individuals.

Assisted reproductive technologies (ARTs)

ARTs are medical procedures that involve laboratory manipulation of sperm and ova to produce a pregnancy. When other treatments have failed, ARTs can help couples with a wide range of fertility issues get pregnant. ARTs can have a number of drawbacks, such as a potentially high cost and procedural invasiveness that may be emotionally and physically taxing for couples. Complications, including multiple pregnancies, are a possibility, so ARTs may therefore not be appropriate for all couples. 

Reproductive Supplements LAMININE and OMEGA+++ for Male Infertility

Because the aforementioned standard procedures come with their own advantages and disadvantages, male reproductive supplements have been studied as a possible treatment method that is non-invasive, more financially accessible, and doesn’t bring about any unwanted side effects. LifePharm's LAMININE and OMEGA+++ are two such supplements, and in a recently concluded study, it was shown that these two supplements are able to provide the nutrients that help with male fertility.

LAMININE and OMEGA+++ and how they work

LAMININE is a supplement for stem cell regeneration that regulates the activity of several genes in the body to support cell differentiation, proliferation, and survival in nearly all organ systems. These mechanisms lessen the stress on the body and are linked to good aging. OMEGA+++ is a multi-action supplement intended to support and enhance circulatory health.

In the context of male infertility, stem cell regeneration may be able to replace lost sperm cells and repair damaged tissue in the testicles. The promotion of circulatory health is crucial for the transport of oxygen and nutrients to the testicles, where sperm are produced. It also helps regulate the temperature of the testicles and maintain it at an optimal level for sperm production. These mechanisms all together ensure the presence of sperm in the ejaculate, increase their quantity and motility, and promote their normal morphology.

Effectivity of LAMININE and OMEGA+++ supplements for male infertility

In a placebo-controlled study conducted by Tikhomirov and colleagues, patients who had undergone unsuccessful fertility treatments were divided into the treatment group and the placebo or "sugar pill" group. The participants in the treatment group took one LAMININE and one OMEGA+++ in the morning, and again at night, for three months.

At the end of the study, the participants from the treatment group showed improved spermogram results as compared to the placebo group, with noted positive changes in sperm quality, viability, and motility. 20% of the participants in the treatment group achieved pregnancy. The supplements were well-tolerated by the participants, and no adverse side effects were reported.

Getting Started with LAMININE and OMEGA+++

Talk to your physician if you believe that you will benefit from reproductive supplements. Learn more about LAMININE and OMEGA+++ on our website today.

About the Author

Dr. Ali is a medical journalist and copywriter at HealthcarePropulsion.com.

References

Centers for Disease Control and Prevention (CDC). Infertility FAQs. Infertility | Reproductive Health | CDC. https://www.cdc.gov/reproductivehealth/infertility/index.htm. Published March 1, 2022.

Dabaja AA, Schlegel PN. Medical treatment of male infertility. Transl Androl Urol. 2014;3(1):9-16.

Dubé E, Cyr DG. The blood-epididymis barrier and human male fertility. Adv Exp Med Biol. 2012;763:218-236.

Durairajanayagam D. Lifestyle causes of male infertility. Arab J Urol. 2018;16(1):10-20. Published 2018 Feb 13.

Emokpae MA, Brown SI. Effects of lifestyle factors on fertility: practical recommendations for modification. Reprod Fertil. 2021;2(1):R13-R26. Published 2021 Jan 8.

Hanson BM, Kaser DJ, Franasiak JM. Male Infertility and the Future of In Vitro Fertilization. Urol Clin North Am. 2020;47(2):257-270.

Kumar N, Singh AK. Trends of male factor infertility, an important cause of infertility: A review of literature. J Hum Reprod Sci. 2015;8(4):191-196.

Leslie SW, Soon-Sutton TL, Khan MAB. Male Infertility. In: StatPearls. Treasure Island (FL): StatPearls Publishing; November 28, 2022.

Mehta A, Nangia AK, Dupree JM, Smith JF. Limitations and barriers in access to care for male factor infertility. Fertil Steril. 2016;105(5):1128-1137.

Sagaradze G, Monakova A, Basalova N, Popov V, Balabanyan V, Efimenko A. Regenerative medicine for male infertility: A focus on stem cell niche injury models. Biomed J. 2022;45(4):607-614.

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